Have you ever watched your child or grandchild bounce around the room and wondered, “Where in the world does he get ALL that energy!” It turns out you have the molecule nicotinamide adenine dinucleotide, or NAD to thank.
Well, at least in part.
You see NAD, a coenzyme of the vitamin niacin, is at the center of energy metabolism. Research has revealed that this molecule plays an important role in fighting off the deterioration of your cell’s energy centers called mitochondria.
And while we don’t entirely understand it yet, mitochondrial breakdown—and the communication issue it causes—is at the heart of aging.1,2 In fact, scientists from Harvard University Medical School and the National Institute on Aging say it’s a driving force behind age-related illnesses from Alzheimer’s to diabetes.3
NAD reverses signs of aging
But NAD could turn out to be the key to putting the brakes on that aging. Animal research suggests increasing your levels of anti-aging NAD doesn’t just slow down the signs of aging, it could even help to reverse some of them! In fact, in a new study at Washington University Medical School researchers did just that.
Researchers literally reduced the signs of aging in mice using NAD-boosting supplements. The new study builds on earlier research in 2003 in which Harvard researchers reversed the deterioration of mice mitochondria, restoring them to a “younger” state with several weeks of nicotinamide mononucleotide (NMN) supplements, a nutrient that boosts NAD levels.1
Restore your youthful energy and metabolism!
Now Washington University Medical School researchers have given another group of older mice their youth back, restoring their metabolism and energy levels with an anti-aging NMN supplement. The NAD-enhancing supplements also suppressed age-related weight gain, improved insulin sensitivity, boosted physical activity, enhanced liver function, increased bone density, improved eye function and even enriched skeletal muscle tone! 4,5
The researchers concluded NMN is an effective anti-aging intervention, and believe it could be useful for older humans too. You see, when we’re younger our bodies make plenty of NAD-boosting NMN on their own. But as we age NMN production plummets, and NAD does right along with it.
NMN is found in a number of foods including broccoli, avocado cucumber and cabbage. Try eating more of these foods in salads, on sandwiches and in smoothies to naturally raise your own NMN levels, and help put the brakes on aging.
NMN supplements are available too, but they’re not many on the market yet to choose from. You probably will not find an NMM supplement in your local health food store, but you should be able to locate one online.
1. “Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging,” Cell, Volume 155 , Issue 7 , 1624 – 1638
2. “Nicotinamide adenine dinucleotide, a metabolic regulator of transcription, longevity and disease,” Curr Opin Cell Biol. 2003 Apr;15(2):241-6.
3. “A New—and Reversible—Cause of Aging,” Harvard Medical School, David Cameron, December 19, 2013, Harvard.edu, Accessed: 10/31/2016
4. “Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice,” Cell Metabolism, Volume 0, Issue 0, Publication stage: In Press Corrected Proof, Accessed: 10/31/2016
5. “Natural compound reduces signs of aging in healthy mice,” News Release: Washington University School of Medicine, October 27, 2016, medicine.wustl.edu, Accessed: 10/31/2016
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